SAME SATISFACTION, FEWER DOWNSIDES
Focus & Clarity
Ceretine™ binds to the same receptors as nicotine, promoting dopamine and acetylcholine.
Sustained Energy
No jitters, no crashes. Just a smooth cognitive boost that lasts.
Mood & Motivation
Ceretine™ lifts mood and drive while L-Theanine keeps you level—no overstimulation, no anxiety.
MORE CONTROL
Lower α6 receptor binding means less compulsive use than nicotine.
We get it — you’re ready for something better than the [CRASH.] [CRAVINGS.] [RELIANCE.] [JITTERS.]
CHOOSE YOUR BUZZ
CERETINE™ + L-THEANINE
The superior nicotine alternative. Designed to deliver nicotine-like satisfaction with fewer downsides.
JOIN 30,000 PEOPLE WHO FOUND THEIR BETTER BUZZ
BUILD YOUR BUNDLE
YOUR FLAVORS, YOUR WAY. SAVE WHEN YOU BUNDLE
ADVISORY BOARD
THE PEOPLE WHO MADE SURE WE WEREN'T FULL OF IT.
DR. RYAN GREENE
Osteopathic Physician, Co-Founder - Monarch Athletic Club
Developed with input from doctors and performance experts - this is the first product in its category that is purpose-driven and backed by science. It's a game changer for professionals, offering the focus and clarity needed to tackle the demands of a busy day with confidence.
SHANE WALLEN
Head Performance Coach, Detroit Tigers
Sett has been an absolute game changer for me. Having never been a nicotine user previously, this product sparked my interest with its unique ceretine and L-theanine blend. I’ve searched far and wide for a product that can get me through a long day coaching on the floor, locking in on programming and administrative work, or getting through longer meetings and calls.
TIM CARON
Co-Founder Allegiate Gym, Fmr. Head Strength Coach Army Football
Nicotine has well-studied benefits for cognition and focus. However, the products through which we consume nicotine can be highly problematic. This is what made me excited to work with Sett. We feel we've improved upon every parameter of traditional nicotine products from a health and performance perspective.
JENNA STAGLAND
MS RD CSSD LD CLT, Dietitian Minnesota Timberwolves | Dietitian Minnesota Wild
Working in professional sports requires me to constantly evaluate products for their performance and recovery benefits. One of my top priorities when selecting products is ensuring they meet strict quality standards.
Frequently asked
questions
How is Sett different from other similar products on the market?
Sett is a first-of-its-kind nicotine alternative that features a synergistic combination of Ceretine™ & L-theanine. Ceretine™ is proprietary compound that is designed to provide nicotine-like satisfaction with fewer downsides. L-theanine has been shown to reduce nicotine induced reward effects via inhibition of the dopamine reward pathway.
What is Ceretine™?
Ceretine™ is a proprietary, patented ingredient designed to deliver the same satisfaction as nicotine with fewer downsides. Ceretine™ is a synthetic alkaloid derived from nicotine acids (b-vitamins). It is similar in structure to nicotine, yet chemically distinct. Ceretine™ works on the same mechanism of action as nicotine. More specifically, Ceretine™ binds to nicotinic-acetycholine receptors (nAChRs) in the brain - thus promoting higher levels of dopamine and acetylcholine in the brain. This mechanism promotes feelings of positive mood, focus, and motivation.
How was Ceretine™ developed?
The story behind Ceretine™ begins in the early 1980s. Big Tobacco was in the midst of a royal-spanking from the health authorities for lying about the health consequences of smoking. There was concern among these companies that nicotine might get banned altogether in the US, so they set out to develop better alternatives to nicotine . Scientists at these companies synthesized more than 20 different ‘nicotine-alternatives’ - some of which had very promising research behind them. As we all know, nicotine was not banned in the US, so for the most part Big Tobacco did their best to bury the evidence around these nicotine alternatives. We believe they did this because they might have actually found compounds that are better than nicotine, and potentially less addictive. 40 years later, our scientists picked up where these folks left off. We identified the most promising of these compounds and conducted our own clinical trials to verify safety and efficacy. Then of course, we had to try the product ourselves. We ran more 15 different test-batches with multiple manufacturing partners to develop our first product - all along the way consulting with our Scientific Advisor Board and sharing our prototypes with fellow high-performing nicotine users to compare effects. What we have created today is a product that is perfectly tailored to the consumer that uses nicotine to be more productive and energized, but doesn’t want to be left feeling anxious and drained after using their pouches. In conjuction with other functional ingredients like L-Theanine, we think you’ll feel better during and after using our pouches. In the long run, our goal is to prove that Ceretine™ is measurably better than nicotine on multiple dimensions, and we are purusing a robust clinical strategy to validate this.
How is Ceretine™ made?
Ceretine™ is produced through a proprietary process of modifications to nicotinic acids (B-vitamins). It is produced in a FDA-registered facility in the United States. This facility is CGMP, and ISO-9001 certified. There are zero tobacco products or derivatives involved in this process.
Is Sett clinically validated?
Ceretine™ has gone through rigorous testing over the last two years, with even more studies planned for the near future. We have performed toxicity studies in vitro and in vivo to confirm that Ceretine™ is not carcinogenic, nor mutagenic, and has a similar toxicity profile to that of nicotine. We have also performed ‘receptor-binding affinity’ studies to measure how exactly Ceretine™ interacts with nAChRs. These studies show that, in aggregate, Ceretine™ has an extremely similar binding affinity to that of nicotine, but interestingly, binds less effectively to the α6 AChR (pronounced ‘Alpha 6’). This specific receptor is believed to play a significant role in nicotine dependence.
Is Ceretine™ addictive?
Given that Ceretine™ works on the same mechanism of action as nicotine, Ceretine™ also has addictive potential. While it is not required for us to place a warning label on our products, we do so to make consumers aware that what they are consuming works in a very similar way to nicotine. As a company, our philosophy is that the habit-forming nature of a product or behavior does not singularly define whether it is good or bad for you. Sugar is addictive, and has basically zero positive side-effects. Exercise can be addictive, yes has almost entirely positive side-effects. Caffeine is addictive, and has both positive and negative side-effects. We view products like Ceretine through a similar lens - it is a tool. It can be used responsibly to be more productive and energized, or you can use it irresponsibly.
What is L-Theanine?
L-Theanine is a natural amino acid found in green tea that promotes relaxation without drowsiness. It supports enhanced focus by blocking excitatory glutamate in the brain and increasing activity of neurotransmitters like GABA. It works synergistically with Ceretine™ to prevent overstimulation.
What kind of experience should I expect when using Sett?
Expect a gradual increase in focus and clarity, with a smooth and sustained energy boost free from jitters, or crash. Unlike nicotine pouches, Sett provides steady cognitive enhancement without sudden peaks or dips.
WHAT MAKES US BETTER.
Functional Ingredients
Ceretine™ and L-Theanine in doses that actually work.
Backed by Experts
We built Sett with doctors and performance experts, not a marketing team.
Label Transparency
Every ingredient, right on the can. No hiding, no fine print.
PH Neutral
Sett's pH is 7.0 —because your gums shouldn't pay the price for your buzz.
